Plant Transcription Factor Database
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G69690.1
Common NameAtTCP15, T6C23.11, TCP15
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family TCP
Protein Properties Length: 325aa    MW: 34752.8 Da    PI: 7.7564
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G69690.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
          TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg.......... 88 
                  ++k+++++++hTkv+gR+RR+R++a caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++  + s +ss s+ s++          
                  789******************************************************************99985555555555444444545566666 PP

          TCP  89 ....kaaksaa.kskksqksaasalnlak 112
                      +++ +++ +++++ +++++ ++ + 
                  55442222222233333333332222222 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036343.1E-4150173IPR005333Transcription factor, TCP
PROSITE profilePS5136928.00852106IPR017887Transcription factor TCP subgroup
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0007623Biological Processcircadian rhythm
GO:0008283Biological Processcell proliferation
GO:0009735Biological Processresponse to cytokinin
GO:0010229Biological Processinflorescence development
GO:0010252Biological Processauxin homeostasis
GO:0031540Biological Processregulation of anthocyanin biosynthetic process
GO:0042023Biological ProcessDNA endoreduplication
GO:0048467Biological Processgynoecium development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009052anatomyflower pedicel
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 325 aa     Download sequence    Send to blast
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.232720.0flower| silique| vegetative tissue
Expression -- Microarray ? help Back to Top
Source ID E-value
Expression AtlasAT1G69690-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in archespores, pollen mother cell, ovule primordia and megaspore mother cells. {ECO:0000269|PubMed:25527103}.
Function -- GeneRIF ? help Back to Top
  1. Together, the two genes, TCP14 and TCP15, influence plant stature by promoting cell division in young internodes.
    [PMID: 21668538]
  2. TCP15 regulates endoreduplication by modulating expression of key cell-cycle genes.
    [PMID: 21992944]
  3. TCP15 regulates the expression of boundary-specific genes through a pathway that affects auxin homeostasis and partially overlaps with the one modulated by class II CIN-like TCP proteins.
    [PMID: 22016421]
  4. Data suggest that responses of leaves and flowers to CK are mediated by SPY-dependent TCP14 and TCP15 activities.
    [PMID: 22267487]
  5. TCP15-dependent transcription is sensitive to oxidative stress.
    [PMID: 23686421]
  6. TCP14 and TCP15 act downstream of the gibberellins and promote seed germination.
    [PMID: 25655823]
  7. DA1, DAR1, and DAR2 physically interact with the transcription factors TCP14 and TCP15, which repress endoreduplication.
    [PMID: 25757472]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
Motif logo
Cis-element ? help Back to Top
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9C9L2
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G69690
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0132890.0AC013289.11 Arabidopsis thaliana chromosome 1 BAC T6C23 genomic sequence, complete sequence.
GenBankAY0563840.0AY056384.1 Arabidopsis thaliana At1g69690/T6C23_11 mRNA, complete cds.
GenBankAY0817060.0AY081706.1 Arabidopsis thaliana At1g69690/T6C23_11 mRNA, complete cds.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_564973.10.0transcription factor TCP15
SwissprotQ9C9L20.0TCP15_ARATH; Transcription factor TCP15
TrEMBLD7KXI20.0D7KXI2_ARALL; Putative uncharacterized protein
STRINGAT1G69690.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP26991230
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
  2. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
  4. Wagner R,Pfannschmidt T
    Eukaryotic transcription factors in plastids--Bioinformatic assessment and implications for the evolution of gene expression machineries in plants.
    Gene, 2006. 381: p. 62-70
  5. Marsch-Martinez N, et al.
    BOLITA, an Arabidopsis AP2/ERF-like transcription factor that affects cell expansion and proliferation/differentiation pathways.
    Plant Mol. Biol., 2006. 62(6): p. 825-43
  6. Aguilar-Martínez JA,Poza-Carrión C,Cubas P
    Arabidopsis BRANCHED1 acts as an integrator of branching signals within axillary buds.
    Plant Cell, 2007. 19(2): p. 458-72
  7. Yadav SR,Prasad K,Vijayraghavan U
    Divergent regulatory OsMADS2 functions control size, shape and differentiation of the highly derived rice floret second-whorl organ.
    Genetics, 2007. 176(1): p. 283-94
  8. Ballvora A, et al.
    Comparative sequence analysis of Solanum and Arabidopsis in a hot spot for pathogen resistance on potato chromosome V reveals a patchwork of conserved and rapidly evolving genome segments.
    BMC Genomics, 2007. 8: p. 112
  9. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
  10. Giraud E, et al.
    TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana.
    Plant Cell, 2010. 22(12): p. 3921-34
  11. Viola IL,Uberti Manassero NG,Ripoll R,Gonzalez DH
    The Arabidopsis class I TCP transcription factor AtTCP11 is a developmental regulator with distinct DNA-binding properties due to the presence of a threonine residue at position 15 of the TCP domain.
    Biochem. J., 2011. 435(1): p. 143-55
  12. Kieffer M,Master V,Waites R,Davies B
    TCP14 and TCP15 affect internode length and leaf shape in Arabidopsis.
    Plant J., 2011. 68(1): p. 147-58
  13. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
  14. Li ZY,Li B,Dong AW
    The Arabidopsis transcription factor AtTCP15 regulates endoreduplication by modulating expression of key cell-cycle genes.
    Mol Plant, 2012. 5(1): p. 270-80
  15. Uberti-Manassero NG,Lucero LE,Viola IL,Vegetti AC,Gonzalez DH
    The class I protein AtTCP15 modulates plant development through a pathway that overlaps with the one affected by CIN-like TCP proteins.
    J. Exp. Bot., 2012. 63(2): p. 809-23
  16. Steiner E, et al.
    The Arabidopsis O-linked N-acetylglucosamine transferase SPINDLY interacts with class I TCPs to facilitate cytokinin responses in leaves and flowers.
    Plant Cell, 2012. 24(1): p. 96-108
  17. Steiner E, et al.
    Class I TCPs modulate cytokinin-induced branching and meristematic activity in tomato.
    Plant Signal Behav, 2012. 7(7): p. 807-10
  18. Viola IL,G
    Redox modulation of plant developmental regulators from the class I TCP transcription factor family.
    Plant Physiol., 2013. 162(3): p. 1434-47
  19. Valsecchi I, et al.
    The intrinsically disordered C-terminal region of Arabidopsis thaliana TCP8 transcription factor acts both as a transactivation and self-assembly domain.
    Mol Biosyst, 2013. 9(9): p. 2282-95
  20. Danisman S, et al.
    Analysis of functional redundancies within the Arabidopsis TCP transcription factor family.
    J. Exp. Bot., 2013. 64(18): p. 5673-85
  21. Kim SH, et al.
    The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity.
    Plant J., 2014. 78(6): p. 978-89
  22. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
  23. Davi
    Class I TCP-DELLA interactions in inflorescence shoot apex determine plant height.
    Curr. Biol., 2014. 24(16): p. 1923-8
  24. We
    Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life.
    Cell Host Microbe, 2014. 16(3): p. 364-75
  25. Chen GH,Sun JY,Liu M,Liu J,Yang WC
    SPOROCYTELESS is a novel embryophyte-specific transcription repressor that interacts with TPL and TCP proteins in Arabidopsis.
    J Genet Genomics, 2014. 41(12): p. 617-25
  26. Resentini F, et al.
    TCP14 and TCP15 mediate the promotion of seed germination by gibberellins in Arabidopsis thaliana.
    Mol Plant, 2015. 8(3): p. 482-5
  27. Peng Y, et al.
    The ubiquitin receptors DA1, DAR1, and DAR2 redundantly regulate endoreduplication by modulating the stability of TCP14/15 in Arabidopsis.
    Plant Cell, 2015. 27(3): p. 649-62
  28. Lucero LE, et al.
    TCP15 modulates cytokinin and auxin responses during gynoecium development in Arabidopsis.
    Plant J., 2015. 84(2): p. 267-82
  29. Viola IL,Camoirano A,Gonzalez DH
    Redox-Dependent Modulation of Anthocyanin Biosynthesis by the TCP Transcription Factor TCP15 during Exposure to High Light Intensity Conditions in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 74-85